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Article

Influence of single nucleotide polymorphisms (SNPs) in immunoregulatory genes in the morbidity of preterm newborns.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Nov 2021

Ribeiro de Andrade Ramos Bruna, Cosi Bento Giovana Fernanda, Navascues Bernardino Rômulo Augusto, Miot Hélio Amante, Guimarães da Silva Márcia

Abstract excerpt

BACKGROUND: Prematurity is the main cause of perinatal and neonatal morbidity and mortality worldwide. Single nucleotide polymorphisms (SNPs) have been associated with the pathogenesis of morbidities in preterm neonates. We aimed to investigate the association between SNPs in regulatory genes of innate immune response IL1B, IL6, IL6R, IL10, TNFA, TNFRII, TLR2 and TLR4 and neonatal/infant morbidities in preterm...

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Identifiers

PMID: 31744360
DOI: 10.1080/14767058.2019.1689946

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