Article
Interleukin-4 receptor alpha gene variants and allergic disease.
Respiratory research - 1 Jan 2000
Hall I P
Abstract excerpt
The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to the risk of developing asthma in a given individual. A number of polymorphisms have been described within the IL-4 receptor alpha (IL-4Ralpha) gene. In addition polymorphism occurs in the promoter for the IL-4 gene...
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