Article
Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.
The Journal of allergy and clinical immunology - 1 Mar 2004
Hoffjan Sabine, Ostrovnaja Irina, Nicolae Dan, Newman Dina L, Nicolae Raluca, Gangnon Ronald, Steiner Lori, Walker Karen, Reynolds Rebecca, Greene Deborah, Mirel Daniel, Gern James E, Lemanske Robert F, Ober Carole
Abstract excerpt
BACKGROUND: Asthma is a chronic respiratory disease that often originates in early childhood. Although candidate gene studies have identified many potential asthma susceptibility genes in adult populations, few have studied associations with immune phenotypes in the first year that might be early clinical markers of asthma. OBJECTIVE: The aim of this study was to assess the contribution of genetic variation to...
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