Article
Role of interleukin-4 genetic polymorphisms and environmental factors in the risk of asthma in children.
Genetics and molecular research : GMR - 3 Nov 2016
Li L, Li Y, Zeng X C, Li J, Du X Y
Abstract excerpt
Asthma is an allergic disease characterized by hyperresponsiveness and chronic inflammation of the airway. The interleukin-4 (IL-4) gene and its single nucleotide polymorphisms are associated with asthma susceptibility in children. A case-control study was performed to evaluate the relationship between asthma risk and the IL-4 rs2243250 (589 C/T) and rs2070874 (107 T/C), and IL-4 receptor (IL-4R) rs1801275 (576...
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