Article
Clonal diversification of primary BALB/c plasmacytomas harboring T(12;15) chromosomal translocations.
Leukemia - 1 May 2000
Kovalchuk A L, Mushinski E B, Janz S
Abstract excerpt
DNA sequence analysis of PCR amplified Igh/c-myc junction fragments of T(12;15) chromosome translocations and immunohistochemical determination of immunoglobulin isotype production were employed to study the clonal diversification of neoplastic translocated plasma cells that resided in peritoneal inflammatory granulomas of BALB/c mice harboring primary plasmacytomas. The diversity of plasma cells was found to...
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