Article
Isolation and molecular characterization of the B cells producing the paraprotein in a case of benign monoclonal gammapathy in C57BL mice.
European journal of immunology - 1 Aug 1991
Bos N A, Meeuwsen C G, De Glopper-Van der Veer E, van den Akker T W, Radl J, Zwaagstra K A, Benner R
Abstract excerpt
Benign monoclonal gammapathy (BMG) is defined as a benign monoclonal B cell proliferative disorder characterized by the presence of a persisting component of homogenous immunoglobulins (H-Ig) in the serum. A possible role of antigenic stimulation in the development of BMG has been suggested. From a C57BL mouse, a murine model for BMG, we have isolated clonally related B cells in order to investigate the...
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