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Article

Insertion of Myc into Igh accelerates peritoneal plasmacytomas in mice.

Cancer research - 1 Sept 2005

Park Sung Sup, Shaffer Arthur L, Kim Joong Su, duBois Wendy, Potter Michael, Staudt Louis M, Janz Siegfried

Abstract excerpt

Gene-targeted mice that contain a His6-tagged mouse c-Myc cDNA, Myc(His), inserted head to head into different sites of the mouse immunoglobulin heavy-chain locus, Igh, mimic the chromosomal T(12;15)(Igh-Myc) translocation that results in the activation of Myc in the great majority of mouse plasmacytomas. Mice carrying Myc(His) just 5' of the intronic heavy-chain enhancer Emu (strain iMyc(Emu)) provide a specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16140930
DOI: 10.1158/0008-5472.CAN-05-1222

Genes

GALT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Insertion of Myc into Igh accelerates peritoneal plasmacytomas in mice.PMID 16140930Read ↗

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