Chromosomal translocations deregulating c-myc are associated with normal immune responses.

doi:10.1038/sj.onc.1201156

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Article

Chromosomal translocations deregulating c-myc are associated with normal immune responses.

Oncogene - 26 Jun 1997

Roschke V, Kopantzev E, Dertzbaugh M, Rudikoff S

Abstract excerpt

Plasmacytomas induced in BALB/c mice by pristane consistently evidence chromosomal translocations involving the c-myc gene and one of the Ig loci. This observation has lead to the suggestion that c-myc deregulation is a critical event in the generation of such tumors. However, it is not clear whe...

Topics

Animals
Base Sequence
Cholera Toxin
Female
Genes, myc
Genetic Predisposition to Disease
Immunization
Immunoglobulin A
Mice
Mice, Inbred BALB C
Mice, Inbred DBA
Molecular Sequence Data
Plasmacytoma
Translocation, Genetic

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