Article
Chromosomal translocations deregulating c-myc are associated with normal immune responses.
Oncogene - 26 Jun 1997
Roschke V, Kopantzev E, Dertzbaugh M, Rudikoff S
Abstract excerpt
Plasmacytomas induced in BALB/c mice by pristane consistently evidence chromosomal translocations involving the c-myc gene and one of the Ig loci. This observation has lead to the suggestion that c-myc deregulation is a critical event in the generation of such tumors. However, it is not clear whether c-myc translocation is related to pristane treatment or occurs in normal lymphocyte populations nor whether such...
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