Genomic instability in B-cells and diversity of recombinations that activate c-myc.

doi:10.1007/978-3-642-79275-5_43

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Article

Genomic instability in B-cells and diversity of recombinations that activate c-myc.

Current topics in microbiology and immunology - 1 Jan 1995

Janz S, Jones G M, Müller J R, Potter M

Abstract excerpt

Genetic rearrangements activating the proto-oncogene c-myc comprise a mandatory oncogenic step in plasma cell tumor development in BALB/cAnPt mice. In the majority of plasmacytomas, c-myc activating rearrangements take the form of reciprocal chromosomal translocations t(12;15) that juxtapose c-my...

Topics

Animals
B-Lymphocytes
DNA Repair
DNA, Neoplasm
Gene Expression Regulation
Gene Rearrangement, B-Lymphocyte
Genes, Switch
Genes, myc
Genetic Predisposition to Disease
Granuloma
Immunoglobulin Heavy Chains
Mice
Mice, Inbred BALB C
Peritonitis
Plasmacytoma
Polymerase Chain Reaction
Precancerous Conditions
Recombination, Genetic

Source

Open in PubMed

Identifiers

PMID: 7895512
DOI: 10.1007/978-3-642-79275-5_43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7895512-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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