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Article

Genomic instability in B-cells and diversity of recombinations that activate c-myc.

Current topics in microbiology and immunology - 1 Jan 1995

Janz S, Jones G M, Müller J R, Potter M

Abstract excerpt

Genetic rearrangements activating the proto-oncogene c-myc comprise a mandatory oncogenic step in plasma cell tumor development in BALB/cAnPt mice. In the majority of plasmacytomas, c-myc activating rearrangements take the form of reciprocal chromosomal translocations t(12;15) that juxtapose c-myc to the immunoglobulin heavy chain alpha locus (IgH alpha) in particular the switch alpha region (S alpha). The...

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Source

Identifiers

PMID: 7895512
DOI: 10.1007/978-3-642-79275-5_43

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genomic instability in B-cells and diversity of recombinations that activate c-myc.PMID 7895512Read ↗

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