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Article

A single amino acid change in the murine leukemia virus capsid gene responsible for the Fv1(nr) phenotype.

Journal of virology - 1 Jun 2000

Jung Y T, Kozak C A

Abstract excerpt

The nr allele at the mouse Fv1 restriction locus governs resistance to B-tropic and some N-tropic murine leukemia viruses (MLVs). Sequence analysis and site-specific mutagenesis of N-tropic MLVs identified a single amino acid difference responsible for this restriction that is distinct from the site that governs N or B tropism. Viruses with other substitutions at this site were evaluated for altered replication...

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Identifiers

PMID: 10799620
DOI: 10.1128/jvi.74.11.5385-5387.2000
PMCID: PMC110898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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