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Article

Capsid Processing Requirements for Abrogation of Fv1 and Ref1 Restriction

28 Jul 2005

Abstract excerpt

Murine leukemia virus is restricted in mouse cells lines by a host factor known as Fv1 and in human cell lines by Ref1. Genetic evidence indicates that these restriction factors target the virus capsid (CA) protein. Restriction can be overcome by adding virus at a high multiplicity of infection, indicating that the restriction factors can be saturated. Cells preexposed to restricted virus will allow infection by...

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Identifiers

PMID: 16051849
DOI: 10.1128/jvi.79.16.10571-10577.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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