Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance.

doi:10.1006/viro.1996.0604

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Article

Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance.

Virology - 15 Nov 1996

Kozak C A, Chakraborti A

Abstract excerpt

The mouse Fv1 genetic locus controls resistance to subgroups of ecotropic, MCF, and amphotropic murine leukemia viruses (MuLVs). In addition to the four previously defined alleles of Fv1 (Fv1(n), Fv1(b), Fv1(nr), Fv1(0)), we present evidence that the novel restriction pattern characteristic of DB...

Topics

Alleles
Animals
Capsid
Drug Resistance
Gene Targeting
Genes, Viral
Leukemia Virus, Murine
Mice
Mutagenesis, Site-Directed
Point Mutation
Viral Envelope Proteins

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