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Article

Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance.

Virology - 15 Nov 1996

Kozak C A, Chakraborti A

Abstract excerpt

The mouse Fv1 genetic locus controls resistance to subgroups of ecotropic, MCF, and amphotropic murine leukemia viruses (MuLVs). In addition to the four previously defined alleles of Fv1 (Fv1(n), Fv1(b), Fv1(nr), Fv1(0)), we present evidence that the novel restriction pattern characteristic of DBA/2J mice maps to the Fv1 locus and therefore represents a novel allele, here designated Fv1(d). Previous studies had...

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Identifiers

PMID: 8918916
DOI: 10.1006/viro.1996.0604

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