Article
Identification of the regions of Fv1 necessary for murine leukemia virus restriction.
Journal of virology - 1 Jun 2001
Bishop K N, Bock M, Towers G, Stoye J P
Abstract excerpt
The Fv1 gene restricts murine leukemia virus replication via an interaction with the viral capsid protein. To study this interaction, a number of mutations, including a series of N-terminal and C-terminal deletions, internal deletions, and a number of single-amino-acid substitutions, were introduced into the n and b alleles of the Fv1 gene and the effects of these changes on virus restriction were measured. A...
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