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Article

Insulin-like growth factor I receptor signaling in differentiation of neuronal H19-7 cells.

Cancer research - 15 Apr 2000

Morrione A, Romano G, Navarro M, Reiss K, Valentinis B, Dews M, Eves E, Rosner M R, Baserga R

Abstract excerpt

The type I insulin-like growth factor receptor (IGF-IR) is known to send two seemingly contradictory signals inducing either cell proliferation or cell differentiation, depending on cell type and/or conditions. H19-7 cells are rat hippocampal neuronal cells immortalized by a temperature-sensitive SV40 large T antigen that grow at 34 degrees C in epidermal growth factor or serum but differentiate at 39 degrees C...

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PMID: 10786694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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