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Article

A dominant role of the juxtamembrane region of the TrkA nerve growth factor receptor during neuronal cell differentiation.

The Journal of biological chemistry - 12 Sept 1997

Yoon S O, Soltoff S P, Chao M V

Abstract excerpt

All receptor tyrosine kinases share a common intracellular signaling machinery, including ras activation, whereas cellular responses vary from mitogenesis to cell differentiation. To investigate the structural basis for receptor tyrosine kinase action for nerve growth factor, the juxtamembrane region of TrkA was transferred to a corresponding region of the epidermal growth factor (EGF) receptor. The resulting...

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Identifiers

PMID: 9287331
DOI: 10.1074/jbc.272.37.23231

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A dominant role of the juxtamembrane region of the TrkA nerve growth factor receptor during neuronal cell differentiation.PMID 9287331Read ↗

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