Article
Recurrent fallopian tube carcinoma: TP53 mutation and clinical course.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Apr 2000
Hellström A C, Blegen H, Malec M, Silfverswärd C, Lystad S, Børresen-Dale A L, Auer G
Abstract excerpt
Primary fallopian tube carcinoma is a rare, aggressive gynecological cancer; little is known about its cause. Previous studies have indicated that p53 immunopositivity is correlated with short-term survival in primary fallopian tube carcinoma. We examined p53 and p21/WAF1 immunostaining and TP53 mutation in exons 5 to 8 by single-stranded conformation polymorphism and constant denaturant gel electrophoresis in...
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