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Article

p53 gene mutations in esophageal cancer detected by polymerase chain reaction single-strand conformation polymorphism analysis.

Japanese journal of cancer research : Gann - 1 Jun 1992

Tamura G, Maesawa C, Suzuki Y, Satodate R, Ishida K, Saito K

Abstract excerpt

Mutations of the p53 gene play an important role in the development of common human malignancies. We investigated mutations of this gene in 26 surgical specimens of esophageal cancer using the polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) analysis. The results were correlated with histological findings, DNA ploidy and the short-term relapse of the disease. PCR-SSCP analysis detected...

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Identifiers

PMID: 1644659
DOI: 10.1111/j.1349-7006.1992.tb00125.x
PMCID: PMC5918882

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Source receipt: pubmed, retrieved 7 Sept 2026.

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