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Article

TP53 overexpression in recurrent endometrial carcinoma.

Gynecologic oncology - 1 Feb 2006

Pijnenborg Johanna M A, van de Broek Leonie, Dam de Veen Geeske C, Roemen Guido M J M, de Haan Jelte, van Engeland Manon, Voncken Jan Willem, Groothuis Patrick G

Abstract excerpt

OBJECTIVE: To study alterations within the p53 pathway in relation to the development of recurrent stage I endometrioid endometrial carcinoma. METHODS: Paraffin-embedded tumor tissue of both primary and recurrent tumors from 44 patients with and 44 without recurrence was used for immunohistochemical analysis of TP53, hMdm2, P21(Waf1/Cip1) and M30. DNA was extracted, and mutation analysis of p53 (exon 5-8, 11) was...

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Identifiers

PMID: 16271749
DOI: 10.1016/j.ygyno.2005.09.056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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