Article
BRCA-mutation-associated fallopian tube carcinoma: a distinct clinical phenotype?
Obstetrics and gynecology - 1 Dec 2005
Cass Ilana, Holschneider Christine, Datta Nandini, Barbuto Denise, Walts Ann E, Karlan Beth Y
Abstract excerpt
OBJECTIVE: To compare clinical and histologic features between fallopian tube cancers in women with germline BRCA mutations and sporadic cases. METHODS: Twenty-eight patients with fallopian tube cancer had BRCA mutation testing using multiplex polymerase chain reaction and protein truncation testing. Histologic slides were reviewed by 2 pathologists, and immunohistochemical staining for p53, ki67, estrogen...
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