Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conditional cell transformation by doxycycline-controlled expression of the ASV17 v-jun allele.

Virology - 25 Apr 2000

Bader A G, Hartl M, Bister K

Abstract excerpt

To investigate the molecular basis of oncogenesis induced by the v-jun oncogene of avian sarcoma virus 17 (ASV17), we developed a conditional cell transformation system in which transcription of the ASV17 v-jun allele is controlled by a doxycycline-sensitive transactivator (tTA) or a reverse (doxycycline-dependent) transactivator (rtTA), respectively. Permanent cell lines of quail embryo fibroblasts conditionally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Avian Sarcoma Viruses
Share to Cell Size
Share to Coturnix

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Doxycycline

Share to Genes, jun

Share to Keratins

Share to Transcriptional Activation

Share to Tumor Stem Cell Assay

Source

Identifiers

PMID: 10772983
DOI: 10.1006/viro.2000.0222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conditional cell transformation by doxycycline-controlled expression of the ASV17 v-jun allele.PMID 10772983Read ↗

Conditional cell transformation by doxycycline-controlled expression of the MC29 v-myc allele.Semantic proximity Read ↗

Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences.Semantic proximity Read ↗

Efficient induction of fibrosarcomas by v-jun requires mutations in the DNA binding region and the transactivation domain.Semantic proximity Read ↗

Jun, the oncoprotein.Semantic proximity Read ↗

Overexpression of avian or mouse c-jun in primary chick embryo fibroblasts confers a partially transformed phenotype.Semantic proximity Read ↗

Jun inhibits myogenic differentiation.Semantic proximity Read ↗

Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: A converging transforming pathway for avian oncovirusesSemantic proximity Read ↗

Analysis of AP-1 function in cellular transformation pathways.Semantic proximity Read ↗

Cellular Transformation and Malignancy Induced by ras Require c-junSemantic proximity Read ↗

Mitogenesis of quiescent chick fibroblasts by v-Src: dependence on events at the membrane leading to early changes in AP-1.Semantic proximity Read ↗

Maf and Jun nuclear oncoproteins share downstream target genes for inducing cell transformation.Semantic proximity Read ↗

Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.