Article
Maf and Jun nuclear oncoproteins share downstream target genes for inducing cell transformation.
The Journal of biological chemistry - 28 Sept 2001
Kataoka K, Shioda S, Yoshitomo-Nakagawa K, Handa H, Nishizawa M
Abstract excerpt
The Maf oncoprotein is a basic leucine zipper (bZip)-bearing transcriptional activator that recognizes the Maf recognition element (MARE) DNA sequence. In this study, we investigated the role of Maf's transactivation function in cell transformation. Replacement of the conserved amino terminus transactivator domain of Maf by a heterologous and stronger transactivator domain (the acidic transactivator domain of...
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