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Article

Jun inhibits myogenic differentiation.

Oncogene - 1 Oct 1991

Su H Y, Bos T J, Monteclaro F S, Vogt P K

Abstract excerpt

Myoblasts from skeletal muscle of chicken or Japanese quail embryos were infected with avian sarcoma virus 17 (ASV-17), a retrovirus carrying the jun oncogene. At high multiplicities of infection ASV-17-induced morphologic transformation inhibited fusion of myoblasts into myotubes and stimulated extended replication. The expression of the muscle-specific proteins desmin, myosin and creatine phosphokinase was...

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Identifiers

PMID: 1656361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Jun inhibits myogenic differentiation.PMID 1656361Read ↗

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Conditional cell transformation by doxycycline-controlled expression of the ASV17 v-jun allele.Semantic proximity Read ↗

Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences.Semantic proximity Read ↗

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A temperature-conditional mutant of simian virus 40 large T antigen requires serum to inhibit myogenesis and does not induce DNA synthesis in myotubes.Semantic proximity Read ↗

Transcriptional down-regulation of myogenin expression is associated with v-ras-induced block of differentiation in unestablished quail muscle cells.Semantic proximity Read ↗

Characterization of heterokaryons between skeletal myoblasts and somatic cells formed by fusion with HVJ (Sendai virus); effects on myogenic differentiation.Semantic proximity Read ↗

Characterization of myogenin expression in myotubes derived from quail myoblasts transformed with a temperature sensitive mutant of Rous sarcoma virus.Semantic proximity Read ↗

The oncogenicity of Jun.Semantic proximity Read ↗

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v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent haematopoietic progenitors.Semantic proximity Read ↗

Transformation blocks differentiation-induced inhibition of serum response factor interactions with serum response elements.Semantic proximity Read ↗

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