Article
Mitogenesis of quiescent chick fibroblasts by v-Src: dependence on events at the membrane leading to early changes in AP-1.
Oncogene - 1 Jul 1993
Catling A D, Wyke J A, Frame M C
Abstract excerpt
Activation of rapidly reversible temperature-sensitive (ts) v-Src in quiescent chicken embryo fibroblasts (CEFs) results in both morphological transformation and exit from G0 to G1, resulting in mitosis. This phenomenon permits examination of cellular responses very soon after activating the onco...
Topics
- Animals
- Base Sequence
- Cell Division
- Cell Membrane
- Chick Embryo
- DNA
- Fibroblasts
- Gene Expression
- Genes, fos
- Genes, jun
- Molecular Sequence Data
- Mutation
- Oncogene Protein pp60(v-src)