Article
Jun, the oncoprotein.
Oncogene - 30 Apr 2001
Vogt P K
Abstract excerpt
Cellular Jun (c-Jun) and viral Jun (v-Jun) can induce oncogenic transformation. For this activity, c-Jun requires an upstream signal, delivered by the Jun N-terminal kinase (JNK). v-Jun does not interact with JNK; it is autonomous and constitutively active. v-Jun and c-Jun address overlapping but not identical sets of genes. Whether all genes essential for transformation reside within the overlap of the v-Jun and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
