Article
Role of cAMP-dependent protein kinase during growth and early development of Dictyostelium discoideum.
Developmental biology - 1 May 2000
Primpke G, Iassonidou V, Nellen W, Wetterauer B
Abstract excerpt
cAMP-dependent protein kinase (PKA) is an essential regulator of gene expression and cell differentiation during multicellular development of Dictyostelium discoideum. Here we show that PKA activity also regulates gene expression during the growth phase and at the transition from growth to development. Overexpression of PKA leads to overexpression of the discoidinIgamma promoter, while expression of the...
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