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Immunological characterization of C3H mice congenic for Fas(lprcg), C3h/HeJ-Fas(lprcg)/Fas(lprcg).

Laboratory animals - 1 Jan 2000

Yasuda T, Zhang Y, Nagase H, Kaneko T, Sayama K, Hashimoto H, Matsuzawa A

Abstract excerpt

Fas(lpr) (lpr) and Fas(lprcg) (lpr(cg)) are allelic mutations of the Fas gene that is involved in apoptosis or programmed cell death. Lpr greatly reduces the expression of functional Fas and lpr(cg) expresses the death domain-disabled, non-functional Fas on the cell surface. C3H/HeJ mice congenic for lpr(cg) (C3H-lpr(cg)) were established and compared with C3H/HeJ-lpr/lpr (C3H-lpr) mice for their immunological...

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PMID: 10759366
DOI: 10.1258/002367700780578019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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