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Article

Distinctive expression of lprcg in the heterozygous state on different genetic backgrounds.

Cellular immunology - 15 Apr 1993

Ogata Y, Kimura M, Shimada K, Wakabayashi T, Onoda H, Katagiri T, Matsuzawa A

Abstract excerpt

Much knowledge of the etiopathogenesis of human autoimmune diseases has been obtained from the mutant mouse models carrying lpr and gld. These autoimmune genes have been regarded as autosomal recessive. The novel lymphoproliferative and autoimmune mutation lprcg is unique in its interaction with gld despite their different chromosomal locations: chromosomes 19 and 1, respectively. Both lprcg and lpr mutations are...

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Identifiers

PMID: 8495493
DOI: 10.1006/cimm.1993.1093

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