Article
Distinctive expression of lprcg in the heterozygous state on different genetic backgrounds.
Cellular immunology - 15 Apr 1993
Ogata Y, Kimura M, Shimada K, Wakabayashi T, Onoda H, Katagiri T, Matsuzawa A
Abstract excerpt
Much knowledge of the etiopathogenesis of human autoimmune diseases has been obtained from the mutant mouse models carrying lpr and gld. These autoimmune genes have been regarded as autosomal recessive. The novel lymphoproliferative and autoimmune mutation lprcg is unique in its interaction with...
Topics
- Animals
- Antibodies, Antinuclear
- Antigen-Antibody Complex
- Autoimmune Diseases
- Disease Models, Animal
- Female
- Gene Expression Regulation
- Heterozygote
- Immunoglobulins
- Kidney Glomerulus
- Lymph Nodes
- Male
