Article
Vasculitis-susceptible genes in mice with a deficit in Fas-mediated apoptosis.
International journal of cardiology - 1 Oct 1998
Nose M, Terada M, Nishihara M, Kamogawa J, Miyazaki T, Mori S, Nishimura M, Wang Y, Kamoto T, Hiai H
Abstract excerpt
Autoimmune diseases show complex pathological manifestations, which frequently involve systemic vasculitis. This complication is understood to be a manifestation of advanced disease, or to represent distinct entities, restricted by genetic and/or environmental factors. An MRL/Mp strain of mice be...
Topics
- Animals
- Antibodies, Antinuclear
- Apoptosis
- Arthritis
- Autoimmune Diseases
- Disease Models, Animal
- Gene Deletion
- Genetic Markers
- Genetic Predisposition to Disease
- Glomerulonephritis
- Linkage Disequilibrium
- Mice
- Mice, Inbred C3H
- Mice, Inbred MRL lpr
- Microsatellite Repeats
- Sialadenitis
- Vasculitis
- fas Receptor