Article
Joint tests of linkage and association for quantitative traits.
Theoretical population biology - 1 Nov 2001
Allison D B, Neale M C
Abstract excerpt
In this paper we describe various study designs and analytic techniques for testing the joint hypothesis that a genetic marker is both linked to and associated with a quantitative phenotype. Issues of power and sampling are addressed. The distinction between methods that explicitly examine association and those that infer association by examining the distribution of allelic transmissions from a heterozygous...
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