Article
Bayesian mapping of quantitative trait loci under the identity-by-descent-based variance component model.
Genetics - 1 Sept 2000
Yi N, Xu S
Abstract excerpt
Variance component analysis of quantitative trait loci (QTL) is an important strategy of genetic mapping for complex traits in humans. The method is robust because it can handle an arbitrary number of alleles with arbitrary modes of gene actions. The variance component method is usually implemented using the proportion of alleles with identity-by-descent (IBD) shared by relatives. As a result, information about...
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