Article
Complex genetic effects in quantitative trait locus identification: a computationally tractable random model for use in F(2) populations.
Genetics - 1 Jan 2011
Zimmer Daisy, Mayer Manfred, Reinsch Norbert
Abstract excerpt
Methodology for mapping quantitative trait loci (QTL) has focused primarily on treating the QTL as a fixed effect. These methods differ from the usual models of genetic variation that treat genetic effects as random. Computationally expensive methods that allow QTL to be treated as random have been explicitly developed for additive genetic and dominance effects. By extending these methods with a variance...
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