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Article

Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP.

RNA (New York, N.Y.) - 1 Feb 2000

Vagner S, Rüegsegger U, Gunderson S I, Keller W, Mattaj I W

Abstract excerpt

The 3' ends of most eukaryotic pre-mRNAs are generated by 3' endonucleolytic cleavage and subsequent polyadenylation. 3'-end formation can be influenced positively or negatively by various factors. In particular, U1 snRNP acts as an inhibitor when bound to a 5' splice site located either upstream of the 3'-end formation signals of bovine papilloma virus (BPV) late transcripts or downstream of the 3'-end...

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Identifiers

PMID: 10688357
DOI: 10.1017/s1355838200991854
PMCID: PMC1369904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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