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Article

Are U4 small nuclear ribonucleoproteins involved in polyadenylation?

Nature - 1 Jan 2000

Berget S M

Abstract excerpt

The mechanism whereby eukaryotic pre-messenger RNAs are polyadenylated is unknown. Most models for polyadenylation invoke cleavage of precursor transcripts at the site of poly(A) addition followed by polymerization of A residues by poly(A) polymerase. Analysis of the sequences surrounding poly(A) addition sites has identified the consensus recognition sequence element AAUAAA as necessary but not sufficient for...

Topics

Base Sequence
Genes, Viral
Humans
Mutation
Nucleic Acid Conformation
Nucleic Acid Hybridization
Poly A
Ribonucleoproteins
Ribonucleoproteins, Small Nuclear
Simian virus 40

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 6325940
DOI: 10.1038/309179a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6325940-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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