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Article

Are U4 small nuclear ribonucleoproteins involved in polyadenylation?

Nature - 1 Jan 2000

Berget S M

Abstract excerpt

The mechanism whereby eukaryotic pre-messenger RNAs are polyadenylated is unknown. Most models for polyadenylation invoke cleavage of precursor transcripts at the site of poly(A) addition followed by polymerization of A residues by poly(A) polymerase. Analysis of the sequences surrounding poly(A) addition sites has identified the consensus recognition sequence element AAUAAA as necessary but not sufficient for...

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PMID: 6325940
DOI: 10.1038/309179a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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