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Article

Splicing of human immunodeficiency virus RNA is position-dependent suggesting sequential removal of introns from the 5' end.

Nucleic acids research - 1 Jan 2005

Bohne Jens, Wodrich Harald, Kräusslich Hans-Georg

Abstract excerpt

Transcription of the HIV-1 genome yields a single primary transcript, which is alternatively spliced to >30 mRNAs. Productive infection depends on inefficient and regulated splicing and appears to proceed in a tight 5' to 3' order. To analyse whether sequential splicing is mediated by the quality of splice sites or by the position of an intron, we inserted the efficient beta-globin intron (BGI) into the 3' region...

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Identifiers

PMID: 15701754
DOI: 10.1093/nar/gki185
PMCID: PMC549389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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