Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the sigma(1) receptor gene in schizophrenia: An association study.

American journal of medical genetics - 7 Feb 2000

Ohmori O, Shinkai T, Suzuki T, Okano C, Kojima H, Terao T, Nakamura J

Abstract excerpt

Possible involvement of sigma receptors in the pathogenesis of schizophrenia has been suggested. In this study we searched systematically for polymorphisms in the 5'-franking region of the sigma(1) receptor. Genetic variation in this region could reduce the expression of the gene, and this suggestion is compatible with findings of reduced sigma binding sites in several cortical regions of schizophrenia. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Gene Frequency

Share to Polymorphism, Single-Stranded Conformational

Share to Schizophrenia

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 10686564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the sigma(1) receptor gene in schizophrenia: An association study.PMID 10686564Read ↗

Lack of association between sigma receptor gene variants and schizophrenia.Semantic proximity Read ↗

No association between the sigma receptor type 1 gene and schizophrenia: results of analysis and meta-analysis of case-control studies.Semantic proximity Read ↗

Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia.Semantic proximity Read ↗

Sigma receptor type 1 gene variation in a group of Polish patients with Alzheimer's disease and mild cognitive impairment.Semantic proximity Read ↗

Functional polymorphisms in the sigma1 receptor gene associated with alcoholism.Semantic proximity Read ↗

A variant of the sigma receptor type-1 gene is a protective factor for Alzheimer disease.Semantic proximity Read ↗

Supportive evidence for the association between the Gln2Pro polymorphism in the SIGMAR1 gene and schizophrenia in the Japanese population: a case-control study and an updated meta-analysis.Semantic proximity Read ↗

Association between a variant of the sigma-1 receptor gene and Alzheimer's disease.Semantic proximity Read ↗

The SIGMAR1 gene is associated with a risk of schizophrenia and activation of the prefrontal cortex.Semantic proximity Read ↗

The Impact of a Single Nucleotide Polymorphism in SIGMAR1 on Depressive Symptoms in Major Depressive Disorder and Bipolar Disorder.Semantic proximity Read ↗

Novel polymorphisms of the AP-2 gene (6p24): analysis of association with schizophrenia.Semantic proximity Read ↗

Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.