Article
No association between the sigma receptor type 1 gene and schizophrenia: results of analysis and meta-analysis of case-control studies.
BMC psychiatry - 21 Oct 2003
Uchida Naohiko, Ujike Hiroshi, Nakata Kenji, Takaki Manabu, Nomura Akira, Katsu Takeshi, Tanaka Yuji, Imamura Takaki, Sakai Ayumu, Kuroda Shigetoshi
Abstract excerpt
BACKGROUND: Several lines of evidence have supported possible roles of the sigma receptors in the etiology of schizophrenia and mechanisms of antipsychotic efficacy. An association study provided genetic evidence that the sigma receptor type 1 gene (SIGMAR1) was a possible susceptibility factor f...
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