Article
Association between a variant of the sigma-1 receptor gene and Alzheimer's disease.
Neuroscience letters - 31 May 2012
Fehér Ágnes, Juhász Anna, László Anna, Kálmán János, Pákáski Magdolna, Kálmán János, Janka Zoltán
Abstract excerpt
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with complex etiology and strong genetic predisposition. A number of investigations support the possible involvement of sigma non-opioid intracellular receptor 1 (SIGMAR1) in the pathophysiology of AD. We aimed to investigate th...
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