Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IS911 transposition is regulated by protein-protein interactions via a leucine zipper motif.

Journal of molecular biology - 25 Feb 2000

Haren L, Normand C, Polard P, Alazard R, Chandler M

Abstract excerpt

Efficient intermolecular transposition of bacterial insertion sequence IS911 involves the activities of two element-encoded proteins: the transposase, OrfAB, and a regulatory factor, OrfA. OrfA shares the majority of its amino acid sequence with the N-terminal part of OrfAB. This includes a putative helix-turn-helix and three of four heptads of a leucine zipper motif. OrfA strongly stimulates OrfAB-mediated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catalytic Domain
Share to Dimerization
Share to Genes, Overlapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leucine Zippers

Share to Precipitin Tests

Share to Repetitive Sequences, Nucleic Acid

Share to Transposases

Share to Viral Regulatory and Accessory Proteins

Source

Identifiers

PMID: 10677279
DOI: 10.1006/jmbi.1999.3485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IS911 transposition is regulated by protein-protein interactions via a leucine zipper motif.PMID 10677279Read ↗

Truncated forms of IS911 transposase downregulate transposition.Semantic proximity Read ↗

IS911-mediated intramolecular transposition is naturally temperature sensitive.Semantic proximity Read ↗

IS911-mediated transpositional recombination in vitro.Semantic proximity Read ↗

The role of tandem IS dimers in IS911 transposition.Semantic proximity Read ↗

Functional characterization of the Bari1 transposition system.Semantic proximity Read ↗

Evidence for a role of translational frameshifting in the expression of transposition activity of the bacterial insertion element IS1.Semantic proximity Read ↗

Detection of tetramerization domains in vivo by cooperative DNA binding to tandem lambda operator sites.Semantic proximity Read ↗

Single-stranded DNA intermediates in IS91 rolling-circle transposition.Semantic proximity Read ↗

Defining functional regions of the IS903 transposase.Semantic proximity Read ↗

Vector for IS element entrapment and functional characterization based on turning on expression of distal promoterless genes.Semantic proximity Read ↗

A bifunctional DNA binding region in Tn5 transposase.Semantic proximity Read ↗

Tn5 transposase loops DNA in the absence of Tn5 transposon end sequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.