Article
Single-stranded DNA intermediates in IS91 rolling-circle transposition.
Molecular microbiology - 1 Jan 2001
del Pilar Garcillán-Barcia M, Bernales I, Mendiola M V, de la Cruz F
Abstract excerpt
IS91 displays a number of characteristics unique among insertion sequence (IS) elements, suggesting that it transposes by a novel mechanism called rolling-circle (RC) transposition. We reported previously that IS91 transposase (TnpA) amino acid sequence shares a series of five conserved signatures with A proteins of RC replicating phages, including a pair of invariant tyrosines that catalyse two successive...
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