The role of tandem IS dimers in IS911 transposition.

doi:10.1046/j.1365-2958.2000.01800.x

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Article

The role of tandem IS dimers in IS911 transposition.

Molecular microbiology - 1 Mar 2000

Turlan C, Ton-Hoang B, Chandler M

Abstract excerpt

Using a combined in vivo and in vitro approach, we demonstrated that the transposition products generated by IS911 from a dimeric donor plasmid are different from those generated from a plasmid monomer. When carried by a monomeric plasmid donor, free IS911 transposon circles are generated by intra-IS recombination in which one IS end undergoes attack by the other. These represent transposition intermediates that...

Topics

Bacterial Proteins
DNA Transposable Elements
DNA, Circular
Dimerization
Escherichia coli
Escherichia coli Proteins
Mutation
Plasmids
Recombination, Genetic
Transposases

Source

Open in PubMed

Identifiers

PMID: 10760133
DOI: 10.1046/j.1365-2958.2000.01800.x

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