Article
A bifunctional DNA binding region in Tn5 transposase.
Molecular microbiology - 1 Feb 2008
Gradman Richard J, Ptacin Jerod L, Bhasin Archna, Reznikoff William S, Goryshin Igor Y
Abstract excerpt
Tn5 transposition is a complicated process that requires the formation of a highly ordered protein-DNA structure, a synaptic complex, to catalyse the movement of a sequence of DNA (transposon) into a target DNA. Much is known about the structure of the synaptic complex and the positioning of protein-DNA contacts, although many protein-DNA contacts remain largely unstudied. In particular, there is little evidence...
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