Article
The P9 peptide sidechain specificity of I-Ad.
Immunology letters - 1 Dec 1999
Bartnes K, Li X, Briand J P, Travers P J, Hannestad K
Abstract excerpt
The murine MHC class II variant I-Ad confers susceptibility to herpes simplex virus (HSV)-induced keratitis and relative protection against type 1 diabetes mellitus. The association to these autoimmune diseases appears to be largely determined by the peptide sidechain specificity of the P9 pocket, which we therefore have analyzed in detail. Assessment of T-cell responses and I-Ad binding capacity of position...
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