Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human leukocyte antigen class-I variation is associated with atopic dermatitis: A case-control study.

Human immunology - 1 Aug 2021

Margolis D J, Mitra N, Duke J L, Berna R, Margolis J D, Hoffstad O, Kim B S, Yan A C, Zaenglein A L, Chiesa Fuxench Z, Dinou A, Wasserman J, Tairis N, Mosbruger T L, Ferriola D, Damianos Georgios, Kotsopoulou Ioanna, Monos D S

Abstract excerpt

Atopic dermatitis (AD) is a common immune-medicated skin disease. Previous studies have explored the relationship between Human Leukocyte Antigen (HLA) allelic variation and AD with conflicting results. The aim was to examine HLA Class I genetic variation, specifically peptide binding groove variation, and associations with AD. A case-control study was designed to evaluate HLA class I allelic variation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatitis, Atopic
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Models, Molecular

Share to Odds Ratio

Share to Protein Conformation

Share to Sequence Analysis, DNA

Share to Structure-Activity Relationship

Source

Open in PubMed Open full text

Identifiers

PMID: 33875297
DOI: 10.1016/j.humimm.2021.04.001
PMCID: PMC8238855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human leukocyte antigen class-I variation is associated with atopic dermatitis: A case-control study.PMID 33875297Read ↗

A combination of HLA-DP α and β chain polymorphisms paired with a SNP in the DPB1 3’ UTR region, denoting expression levels, are associated with atopic dermatitisSemantic proximity Read ↗

HLA Class I Polymorphisms Influencing Both Peptide Binding and KIR Interactions Are Associated with Remission among Children with Atopic Dermatitis: A Longitudinal Study.Semantic proximity Read ↗

Association of HLA-DRB1 genetic variants with the persistence of atopic dermatitis.Semantic proximity Read ↗

Role of Human Leukocyte Antigen Class II in Antibody-Mediated Skin Disorders.Semantic proximity Read ↗

Association of KIR Genes and MHC Class I Ligands with Atopic Dermatitis.Semantic proximity Read ↗

HLA in Alzheimer's Disease: Genetic Association and Possible Pathogenic Roles.Semantic proximity Read ↗

Association between polymorphisms and atopic dermatitis susceptibility: A systematic review and meta-analysis.Semantic proximity Read ↗

Amino acid signatures in the HLA class II peptide-binding region associated with protection/susceptibility to the severe West Nile Virus diseaseSemantic proximity Read ↗

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control studySemantic proximity Read ↗

MHC class I associations beyond HLA-B27: the peptide binding hypothesis of psoriatic arthritis and its implications for disease pathogenesis.Semantic proximity Read ↗

Molecular mechanisms of HLA association with autoimmune diseases.Semantic proximity Read ↗

HLA-restricted Biology of Severe Cutaneous Adverse Reactions (SCARs): Dapsone-induced Hypersensitivity as an ExampleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.