Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytokines in genetic susceptibility to multiple sclerosis: a candidate gene approach. French Multiple Sclerosis Genetics Group.

Journal of neuroimmunology - 3 Jan 2000

Reboul J, Mertens C, Levillayer F, Eichenbaum-Voline S, Vilkoren T, Cournu I, Babron M C, Lyon-Caen O, Clerget-Darpoux F, Edan G, Clanet M, Brahic M, Bureau J F, Fontaine B, Liblau R

Abstract excerpt

The immune system is involved in the pathophysiology of multiple sclerosis (MS) but the initiating antigen(s) is not yet identified. Since cytokines control both the intensity and the quality of the immune response they may be relevant candidates for the genetic susceptibility to MS. To analyze the contribution of type 1 and type 2 cytokine and cytokine receptor genes in the genetic susceptibility to MS, we have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to HLA-DR Antigens

Share to HLA-DR Serological Subtypes

Share to Likelihood Functions

Share to Multiple Sclerosis

Share to Receptors, Interleukin-2

Source

Identifiers

PMID: 10626674
DOI: 10.1016/s0165-5728(99)00158-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytokines in genetic susceptibility to multiple sclerosis: a candidate gene approach. French Multiple Sclerosis Genetics Group.PMID 10626674Read ↗

Immune system genes in multiple sclerosis: genetic association and linkage analyses on TCR beta, IGH, IFN-gamma and IL-1ra/IL-1 beta loci.Semantic proximity Read ↗

Genetic predisposition to multiple sclerosis as revealed by immunoprinting.Semantic proximity Read ↗

[Polymorphic variants of the immune response genes as risk factors for primary progressive multiple sclerosis].Semantic proximity Read ↗

Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis.Semantic proximity Read ↗

Multiple sclerosis susceptibility: population and twin study of polymorphisms in the T-cell receptor beta and gamma genes region. French Group on Multiple Sclerosis.Semantic proximity Read ↗

The interferon gene cluster: a candidate region for MS predisposition? Multiple Sclerosis Study Group.Semantic proximity Read ↗

A systematic study of oligodendrocyte growth factors as candidates for genetic susceptibility to MS. French Multiple Sclerosis Genetics Group.Semantic proximity Read ↗

The association of -330 interleukin-2 gene polymorphism and HLA-DR15 allele in Iranian patients with multiple sclerosis.Semantic proximity Read ↗

Occurrence and clinical relevance of an interleukin-4 gene polymorphism in patients with multiple sclerosis.Semantic proximity Read ↗

High frequency of the IL-2 -330 T/HLA-DRB1*1501 haplotype in patients with multiple sclerosis.Semantic proximity Read ↗

No association of three polymorphisms in the alpha-2-macroglobulin and lipoprotein related receptor genes with multiple sclerosis.Semantic proximity Read ↗

An evaluation of interleukin genes fails to identify clear susceptibility loci for multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.