Article
[Polymorphic variants of the immune response genes as risk factors for primary progressive multiple sclerosis].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2000
Popova E V, Kiselev I S, Boyko A N, Sivertseva S A, Malkova N A, Korobko D S, Spirin N N, Kasatkin D S, Karaeva A V, Turova E L, Spirina N N, Volkova L I, Baulina N M, Bashinskaya V V, Kulakova O G, Favorova O O
Abstract excerpt
AIM: To analyze the involvement of immune response genes in the pathogenesis of primary progressive multiple sclerosis (PPMS). MATERIAL AND METHODS: This multicenter study included 111 patients with PPMS from the Russian ethnic group. The association of PPMS with genes of immune system was analyzed by the study of polymorphic variants of genes of cytokines and genes of antigen-presenting cells. RESULTS AND...
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