Article
Immune system genes in multiple sclerosis: genetic association and linkage analyses on TCR beta, IGH, IFN-gamma and IL-1ra/IL-1 beta loci.
Journal of neuroimmunology - 1 Oct 1997
Wansen K, Pastinen T, Kuokkanen S, Wikström J, Palo J, Peltonen L, Tienari P J
Abstract excerpt
The role of genetic factors in the etiology of multiple sclerosis (MS) has been clearly demonstrated but the loci determining susceptibility to this disease remain largely unidentified. A contribution from several immune system genes has been suggested based on animal models and association/linkage analyses on MS patients and families. With the exception of the findings from the HLA complex, studies on candidate...
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