Article
A systematic study of oligodendrocyte growth factors as candidates for genetic susceptibility to MS. French Multiple Sclerosis Genetics Group.
Neurology - 1 Sept 1998
Mertens C, Brassat D, Reboul J, Eichenbaum-Voline S, Vuillemin-Azais C, Cournu I, Babron M C, Semana G, Edan G, Clanet M, Clerget-Darpoux F, Baron-Van Evercooren A, Lyon-Caen O, Liblau R, Fontaine B
Abstract excerpt
OBJECTIVE: To test 23 genes coding for growth factors and their receptors as candidates for MS genetic susceptibility in 84 multiplex families of French origin by linkage analysis. BACKGROUND: Epidemiologic studies have indicated that genetic susceptibility in MS exists. To identify MS susceptibility genes, association and linkage studies were performed with candidate genes suggested by the pathology of MS. The...
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