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Article

Occurrence and clinical relevance of an interleukin-4 gene polymorphism in patients with multiple sclerosis.

Journal of neuroimmunology - 1 Jun 1997

Vandenbroeck K, Martino G, Marrosu M, Consiglio A, Zaffaroni M, Vaccargiu S, Franciotta D, Ruggeri M, Comi G, Grimaldi L M

Abstract excerpt

An epistatic gene interaction has been advocated to explain disease susceptibility in multiple sclerosis (MS). Cytokine genes are possible candidates due to the central role played by cytokines in the regulation of the immune-mediated pathogenetic process leading to central nervous system demyelination in these patients. Since interleukin (IL)-4 gene polymorphisms have been associated with immune-mediated...

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PMID: 9184650
DOI: 10.1016/s0165-5728(97)00058-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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