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Article

No association of three polymorphisms in the alpha-2-macroglobulin and lipoprotein related receptor genes with multiple sclerosis.

Journal of neuroimmunology - 30 Aug 2001

Schweer D, Jacobsen M, Ziegler A, Jäkel S, Oertel W H, Sommer N, Hemmer B

Abstract excerpt

Alpha-2-macroglobulin (A2M) is a proteinase inhibitor involved in deactivation of cytokines and modulation of antigen-mediated immune responses. Based on its role in inflammatory and neurodegenerative disorders, we investigated the role of A2M and its receptor low-density lipoprotein receptor-related protein (LRP) for the development of multiple sclerosis (MS). We analyzed the frequency of two polymorphisms in...

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Source

Identifiers

PMID: 11498265
DOI: 10.1016/s0165-5728(01)00347-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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