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Article

Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1.

Molecular and cellular biology - 1 Jan 2000

Li S, Wang Q, Chakladar A, Bronson R T, Bernards A

Abstract excerpt

Human IQGAP1 is a widely expressed 190-kDa Cdc42-, Rac1-, and calmodulin-binding protein that interacts with F-actin in vivo and that can cross-link F-actin microfilaments in vitro. Recent results have implicated IQGAP1 as a component of pathways via which Cdc42 or Rac1 modulates cadherin-based cell adhesion (S. Kuroda et al., Science 281:832-835, 1998), whereas yeast IQGAP-related proteins have been found to...

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Source

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Identifiers

PMID: 10611248
DOI: 10.1128/MCB.20.2.697-701.2000
PMCID: PMC85173

Genes

IQGAP1
IQGAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1.PMID 10611248Read ↗

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